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HelpTest Code LAB6731 Chagas Disease, Serum
Performing Laboratory
Sent thru Missouri State Health Laboratory to CDC
Specimen Requirements
Patient Preparation: None
Collection Container/Tube
Preferred/Acceptable: Plain red-top tube
Submission Container/Tube:
Specimen Collection Volume: 2.0 mL (minimum 1.0 mL)
Special Instructions: Send a completed "Center for Disease Control Patient History Form" with specimen
Supplemental Information Required
CDC 50.34 Specimen Submission Form must include previous positive serology result on an LDT or FDA cleared/approved test for chronic Chagas disease, exposure and travel history, and other relevant risk factors that include clinical symptoms, and treatment
Sample Rejection
Mislabled or unlabeled specimens
Logistics
Test Availability: Monday-Sunday
Test set-up: Varies
Turnaround Time: 3-4 weeks
Reference Values
Reference Interval:
| Complement fixation diagnostic titer: | >1:8 |
| Indirect fluorescent antibody diagnostic titer: | >1:32 |
Critical Value: None established
Methodology
Antibody Detection, Western blot, Immunoblot, T. cruzi trypomastigote excretory secretory antigens (TESA)
Limitations
- Due to the nature of this antibody detection assay, it cannot determine whether a positive result is a current or previous infection.
Additional Information
FOR SLCH CORE LABORATORY USE ONLY
Lab Processing Instructions: Centrifuge to separate and aliquot sample into a leak-proof, screw-cap, plastic vial for transport.
Processed Volume: 1.0 mL (minimum 0.5 mL) serum
Transport Temperature: Place specimen in 'State Health' box in Central Receiving for pick-up by State Lab courier. Pick-up time is Mon-Fri 1400-1500 and Sunday 1200-1300.Refrigerate overnight and weekends.
Analyte Stability:
| Specimen Type | Temperature | Time |
|---|---|---|
| Whole Blood (unprocessed) | Ambient | NA |
| Serum (processed) | Refrigerated (preferred) | 7 days |
| Ambient | NA | |
| Frozen | 8 weeks |
NOTE: Serum can be stored at refrigerated temperature (2-8°C) for up to 7 days prior to freezing or stored frozen (-20°C or lower) for up to 8 weeks.
Test Classification and CPT Code
Not applicable
LOINC
NA
Last Reviewed
08/2025