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Test Code LAB5749 Soluble IL-2R

Important Note

COLLECT SPECIME FOR RECEIPT IN LAB ON DAY OF COLLECTION BY 16:30 P.M. BUT DO NOT COLLECT BEFORE 10:00 A.M. IF POSSIBLE

Additional Codes

CCH Test ID  
2904000

Performing Laboratory

St. Louis Children's Hospital Sendout to Cincinnati Children's Diagnostic Immunology Laboratory

Specimen Requirements

Patient Preparation: None

Container/Tube  
Preferred/Acceptable:  Lavender-top (EDTA) tube
Collection Volume: 3.0 mL (minimum 1.0 mL)

Submission Container/Tube: If specimen is coming from outside facility, send whole blood in original collection container. Keep specimen at ambient temperature only.

Special Instructions: 

  • Immediately invert tube gently 8-10 times after collection to ensure proper mixing of blood and anticoagulant (this will avoid specimen clotting).
  • Forward promptly at ambient temperature.
  • Complete a "Cincinnati Children's DIL test requistion form" to send with specimen.

Sample Rejection

Mislabeled or unlabeled specimens

Specimens collected in gel separater tubes

Logistics

Test Availability: Monday-Sunday
Cut-off time: 1630

Days set up by performing lab: Monday-Friday
Turnaround Time: 3-5 days

Reference Values

Interpretive Data

Basiliximab binds with the IL2R in vivo. Results for patients on basiliximab reflect the unbound portion of sIL2R.

Reference Interval

Age Range Reference Range
<3 years: 398 - 1940 U/mL
3 - 7 Years: 144 - 1329 U/mL
≥8 Years: 137 – 838 U/mL

Critical Value: None established

Methodology

Chemiluminescence

Limitations

  • NA

Additional Information

FOR SLCH CORE LABORATORY USE ONLY

Lab Processing Instructions: DO NOT SPIN. Send specimen in original vacutainer.

  • NOTE: Keep sample as ambient whole blood for delivery to CCH-DIL lab within 24 hours of collection. If delivery cannot occur within 24 hours, separate plasma/serum from cells within 24 hours of collection. Freeze two 0.5mL plasma/serum aliquots immediately at -20°C or lower. Separated plasma/serum samples must be sent with enough dry ice to maintain a frozen state until received at CCH-DIL.

Processed Volume: 3.0 mL (minimum volume 1.0 mL) Whole Blood

Transport Temperature: Ambient 
Analyte Stability:

Specimen Type Temperature    Time
Whole Blood (unprocessed)     Ambient 24 hours
  Refrigerated     Unacceptable   
  Frozen    

Unacceptable

NOTE: if specimen must be processed it is stable frozen for 6 months.   

NOTE:

  • ship specimen Monday-Thursday only, marking on outside of shipping box "STORE AT ROOM TEMPERATURE-DO NOT REFRIGERATE" and "DELIVER PROMPTLY UPON ARRIVAL".
  • The CCH-DIL operates Mon-Fri, 8:00am to 5:00pm (EST). Testing is not performed and samples cannot be received on weekends/certain holidays. First Overnight shipping is strongly recommended. Please call/fax (513-636-4685/513-636-3861) the tracking number so they may better track specimen.
  • Send a completed "CCH-DIL test requistion" form with specimen.
  • Specimen MUST be received at CCH within 24 hours of collection if sending whole blood (preferred). If unable to make shippment within 24 hours (weekends/holidays; specimen coll prior to 1000 a.m. or missed evening shipping) process specimen as above and freeze for next shipping opportunity and ship frozen on dry ice.
  • Ship samples overnight to:
    •  CCHMC – Julie Beach
    •  DIL – Rm R2328 3333 Burnet Avenue
    •  Cincinnati, OH 45229

Test Classification and CPT Code

83520

LOINC

  • 43171-8

Last Reviewed

08/2025