Test Code LAB494 Rapid Plasma Reagin (RPR), Blood
Testing Algorithm
RPR Quantitative and treponemal antibody confirmation testing will automatically be preformed at an additional charge whenever RPR Qualitative is reactive.
Performing Laboratory
St. Louis Children's Hospital Laboratory - Immunology/Serology
Specimen Requirements
Patient Preparation: None
Collection Container/Tube:
Preferred: Gold SST gel tube
Acceptable: Plain red-top tube or Lavender (EDTA) tube/or microtainer
Submission Container/Tube: If specimen is coming from outside facility and collected in a plain red-top tube or EDTA tube aliquot processed sample into a plastic vial for transport (labeling with specimen type).
Specimen Collection Volume: 2.0 mL (minimum 0.5 mL)
Special Instructions: None
Sample Rejection
Mislabled or unlabeled specimens
Specimen that are grossly hemolyzed and/or grossly turbid
Logistics
Test Availability: Monday-Sunday
Cut-off time: 1300
Turnaround Time: Same Day; next day if received after cut-off
Reference Values
Reference Interval: Non-reactive
Critical Value: None established
NOTE: Physician or nurse will be called with notification of non-critical results that are "Reactive"
Methodology
Flocculation/Particle Agglutination card test
Limitations
- NA
Additional Information
FOR SLCH CORE LABORATORY USE ONLY
Lab Processing Instructions: Centrifuge to separate. If specimen is collected in a plain red-top tube or EDTA tube aliquot sample into screw-cap,plastic vial for testing (labeling aliquot with specimen type).
Processed Volume: minimum 0.1 mL serum (or plasma)
Analyte Stability:
Specimen Type | Temperature | Time |
---|---|---|
Whole Blood (unprocessed) | Ambient | NA |
Plasma/Serum (processed) | Refrigerated (preferred) | 7 days |
Ambient | NA | |
Frozen | NA |
NOTE:
- EDTA plasma is only stable 24 hours
- Do not test specimens that are grossly hemolyzed, contaminated or extremely turbid
- CSF can not be tested by this method
Test Classification and CPT Code
86592
LOINC
20507-0
Last Reviewed
07/2025